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Closures from COVID-19 have affected 1.6 billion children worldwide. Nearly two years into the pandemic, experts say the economic costs are in the trillions and the social costs are incalculable.

Americans' life expectancy dropped for the second year in a row and is the biggest drop since the 1920s. COVID-19 is driving the downward trend, according to CDC data.

Daily mass testing was ordered in the city of Zhengzhou in what the local government called a "war of annihilation" against the virus.

President Biden has tested positive for COVID -- in another setback as he battles mounting questions over his ability to lead and defeat Donald Trump in the 2024 White House race.

With a fast-growing winter surge upon us, self-testing kits remain expensive and hard to find. The reasons go back to the approach the U.S. took from the outset in developing tests.

Psychologist James Jackson says people with long COVID experience impaired brain function and mental health issues. He offers some practical advice and support in his new book, Clearing the Fog.

U.S. flu vaccines were redesigned after an influenza strain disappeared globally. Physical distancing and masking during the early days of COVID likely pushed the strain into oblivion.

Vaccines may not be as effective for those who are immuno-compromised. Protecting them needs to be made a top priority, says researchers — to keep them safe and to slow the emergence of variants.

If approved, this would be the second booster shot Moderna has issued for people ages 18 and up.

It's been a confusing and fast-changing couple of months for rules about getting a COVID shot. It should be a little easier now, after a panel of vaccine advisers met last week.